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Understanding Glioblastoma: Challenges and Advances in Treatment
Glioblastoma, often referred to as glioblastoma multiforme (GBM), is one of the most aggressive and common forms of primary brain tumors in adults. Originating from glial cells, which provide support and insulation for neurons in the central nervous system, glioblastoma is notorious for its rapid growth, invasive nature, and poor prognosis. Despite extensive research, it remains a significant challenge in neuro-oncology.
The symptoms of glioblastoma vary depending on the tumor's location in the brain. Patients often experience headaches, seizures, cognitive or personality changes, and neurological deficits such as weakness or speech difficulties. Because these symptoms overlap with other neurological conditions, early diagnosis is often difficult, and many cases are only identified when the tumor has reached an advanced stage. Magnetic Resonance Imaging (MRI) and computed tomography (CT) scans are commonly used to detect and evaluate the extent of glioblastoma, while biopsy remains the…